NOL7

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOL7 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,366 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NOL7-associated GO terms across cancer lineages are Negative regulation of RNA export from nucleus, Protein peptidyl-prolyl isomerization, and Endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Each is linked with NOL7 in more than 15 cancer types. Because this analysis shows association rather than direction, both NOL7-to-partner and partner-to-NOL7 results are reported.

Each partner links to its own Q-omics profile.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL7→partner) and Y-score (partner→NOL7) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
KIDNEYNegative regulation of RNA export from nucleus →+0.141+0.835<.001<.001316
PANCREASProtein peptidyl-prolyl isomerization →+0.141+0.773<.001<.001313
BLOOD_MyelomaEndonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.132+0.516.005.009213
UPPER_AERODIGESTIVE_TRACTDNA replication initiation →+0.137+0.725.008.002312
BLOOD_MyelomarRNA 5'-end processing →+0.132+0.516.005.009213
UPPER_AERODIGESTIVE_TRACTEndonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA) →+0.119+0.640.003.005311
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,366 associations by consensus.

Exploration