NOL6

Across TCGA patient cohorts, NOL6 mutation is significantly associated with the RNA expression of many other genes, with 4,203 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL6-associated genes across cancer lineages are ELAC2, ATP5F1A, and SAAL1. Each is linked with NOL6 in more than 4 cancer types. Because this analysis shows association rather than direction, both NOL6-to-partner and partner-to-NOL6 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ELAC2 grouped by NOL6-low versus NOL6-high in COAD.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL6→partner) and Y-score (partner→NOL6) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	ELAC2 →	+0.401	+2.455	<.001	.001	3	5
STAD	ATP5F1A →	+0.782	+3.186	<.001	.009	3	4
UCEC	SAAL1 →	+0.460	+2.399	<.001	<.001	3	4
COAD	MRM3 →	+0.493	+2.637	<.001	.005	3	4
COAD	PHF23 →	+0.426	+3.760	<.001	<.001	3	4
UCEC	TIMM21 →	+0.584	+2.389	<.001	<.001	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,203 associations by consensus.

ELAC2 by NOL6 expression — COAD

Explore this box plot interactively →