NOL12

Across TCGA patient cohorts, NOL12 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOL12-associated genes across cancer lineages are CD8+ Tcm, Adipocytes, and MSC. Each is linked with NOL12 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL12-to-partner and partner-to-NOL12 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD8+ Tcm grouped by NOL12-low versus NOL12-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL12→partner) and Y-score (partner→NOL12) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	CD8+ Tcm →	+0.028	+2.350	.004	.031	3	2
UCEC	Adipocytes →	+0.030	+2.144	<.001	.036	3	1
UCEC	MSC →	-0.245	-3.169	.019	.019	2	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD8+ Tcm by NOL12 expression — UCEC

Explore this box plot interactively →