NOL11

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOL11 RNA expression is significantly associated with the go_rna of many other GO terms, with 4,453 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NOL11-associated GO terms across cancer lineages are DNA-templated DNA replication, DNA recombination, and DNA replication. Each is linked with NOL11 in more than 18 cancer types. Because this analysis shows association rather than direction, both NOL11-to-partner and partner-to-NOL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, DNA-templated DNA replication grouped by NOL11-low versus NOL11-high in BONE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL11→partner) and Y-score (partner→NOL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BONEDNA-templated DNA replication →+0.177+0.993<.001<.001319
BONEDNA recombination →+0.110+0.775.001.006319
BONEDNA replication →+0.144+0.964.001.001318
BONEDNA replication initiation →+0.237+0.865<.001.002318
BONERegulation of DNA replication →+0.100+0.836.002.002318
PANCREASDouble-strand break repair →+0.089+1.116<.001<.001318
Each partner links to its Q-omics profile. Showing the 6 strongest of 4,453 associations by consensus.

DNA-templated DNA replication by NOL11 expression — BONE

Box plot of DNA-templated DNA replication in NOL11-low vs NOL11-high samples in BONE.

Explore this box plot interactively →

Exploration