NOL11

Across TCGA cell cohorts, NOL11 mutation is significantly associated with the drug of many other genes, with 10 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOL11-associated genes across cancer lineages are LCL161, Fulvestrant, and SGC-CBP30. Each is linked with NOL11 in more than 1 cancer types. Because this analysis shows association rather than direction, both NOL11-to-partner and partner-to-NOL11 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, LCL161 grouped by NOL11-low versus NOL11-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL11→partner) and Y-score (partner→NOL11) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	LCL161 →	+0.362	+2.646	.026	.047	3	1
LARGE_INTESTINE	Fulvestrant →	+0.363	+2.649	.034	.046	3	1
LARGE_INTESTINE	SGC-CBP30 →	+0.317	+2.649	.024	.046	2	1
LARGE_INTESTINE	PRT062607 →	+0.616	+2.769	.014	.040	2	1
LARGE_INTESTINE	BDILV000379a →	+0.389	+2.649	.010	.046	1	1
LARGE_INTESTINE	CZC24832 →	+0.287	+2.646	.027	.047	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 10 associations by consensus.

LCL161 by NOL11 expression — LARGE_INTESTINE

Explore this box plot interactively →