NOL10

Across TCGA patient cohorts, NOL10 protein abundance is significantly associated with the RNA expression of many other genes, with 22,253 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOL10-associated genes across cancer lineages are WDR43, MYBL2, and TPX2. Each is linked with NOL10 in more than 8 cancer types. Because this analysis shows association rather than direction, both NOL10-to-partner and partner-to-NOL10 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NOL10 versus WDR43 in LSCC, with a Pearson correlation of 0.78.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL10→partner) and Y-score (partner→NOL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	WDR43 →	+0.858	+0.546	<.001	<.001	3	9
GBM	MYBL2 →	+1.430	+0.316	<.001	.001	3	9
CCRCC	TPX2 →	+1.330	+0.256	<.001	<.001	3	9
LSCC	FLI1 →	-0.701	-0.356	<.001	<.001	3	8
GBM	ADRB2 →	-0.986	-0.305	<.001	.001	3	8
LSCC	TOP1MT →	+0.784	+0.355	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 22,253 associations by consensus.

NOL10 vs WDR43 — LSCC

Explore this scatter interactively →