NOL10

RNA expression — cross-omics
Cross-omicsRNA → FUNCTION-RNACell-linePairwise association · TCGA cohorts

Across TCGA cell cohorts, NOL10 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,585 significant associations in total. BLOOD_Lymphoma shows the largest number of these associations.

The most reproducible NOL10-associated GO terms across cancer lineages are Maturation of SSU-rRNA, Nucleolar large rRNA transcription by RNA polymerase I, and DNA-templated DNA replication. Each is linked with NOL10 in more than 18 cancer types. Because this analysis shows association rather than direction, both NOL10-to-partner and partner-to-NOL10 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Maturation of SSU-rRNA grouped by NOL10-low versus NOL10-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOL10→partner) and Y-score (partner→NOL10) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner GO termX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
BLOOD_LymphomaMaturation of SSU-rRNA →+0.119+0.897<.001<.001319
LUNG_NSCLC_LUSCNucleolar large rRNA transcription by RNA polymerase I →+0.145+0.634<.001.001318
UPPER_AERODIGESTIVE_TRACTDNA-templated DNA replication →+0.096+0.735<.001<.001317
OVARYRibosomal small subunit biogenesis →+0.092+0.570<.001<.001316
SOFT_TISSUEDNA replication initiation →+0.166+0.623<.001.004316
UPPER_AERODIGESTIVE_TRACTTranscription by RNA polymerase I →+0.109+0.969<.001<.001316
Each partner links to its Q-omics profile. Showing the 6 strongest of 3,585 associations by consensus.

Maturation of SSU-rRNA by NOL10 expression — BLOOD_Lymphoma

Box plot of Maturation of SSU-rRNA in NOL10-low vs NOL10-high samples in BLOOD_Lymphoma.

Explore this box plot interactively →

Exploration