Across TCGA patient cohorts, NOG mutation is significantly associated with the RNA expression of many other genes, with 212 significant associations in total. COAD shows the largest number of these associations.

The most reproducible NOG-associated genes across cancer lineages are TACC3, OR4C9P, and VN1R79P. Each is linked with NOG in more than 1 cancer types. Because this analysis shows association rather than direction, both NOG-to-partner and partner-to-NOG results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOG→partner) and Y-score (partner→NOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TACC3 →	+0.549	+3.665	.002	.001	3	2
BLCA	OR4C9P →	+0.065	+7.040	<.001	<.001	3	1
BLCA	VN1R79P →	+0.080	+5.251	.006	.006	3	1
COAD	NF2 →	+0.396	+3.250	.005	.008	3	1
COAD	CHP1 →	+0.459	+3.584	.004	.002	3	1
COAD	OR52B6 →	+0.059	+2.568	<.001	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 212 associations by consensus.

Exploration

NOG survival (RNA) · tumor vs normal (RNA) · all NOG data types