Across TCGA cell cohorts, NOG protein abundance is significantly associated with the RNA expression of many other genes, with 3,449 significant associations in total. BONE shows the largest number of these associations.

The most reproducible NOG-associated genes across cancer lineages are XPNPEP3, TAB1, and ZBED4. Each is linked with NOG in more than 5 cancer types. Because this analysis shows association rather than direction, both NOG-to-partner and partner-to-NOG results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOG→partner) and Y-score (partner→NOG) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Myeloma	XPNPEP3 →	+0.927	+0.434	.005	.001	3	6
PANCREAS	TAB1 →	+0.862	+0.498	<.001	<.001	3	5
BONE	ZBED4 →	+1.740	+0.684	.005	.003	3	5
LARGE_INTESTINE	INTS10 →	+0.730	+0.489	.002	.007	2	6
BLOOD_Myeloma	EXOSC9 →	+1.026	+0.482	.002	.002	3	5
BLOOD_Myeloma	LMLN →	+1.815	+0.497	.003	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,449 associations by consensus.

Exploration

NOG survival (RNA) · tumor vs normal (RNA) · all NOG data types