Across TCGA patient cohorts, NOC4L protein abundance is significantly associated with the RNA expression of many other genes, with 17,408 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NOC4L-associated genes across cancer lineages are ABCA8, FOXM1, and CDCA3. Each is linked with NOC4L in more than 8 cancer types. Because this analysis shows association rather than direction, both NOC4L-to-partner and partner-to-NOC4L results are reported.

Each partner links to its own Q-omics profile.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC4L→partner) and Y-score (partner→NOC4L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
PDAC	ABCA8 →	-1.018	-0.250	<.001	<.001	3	9
BRCA	FOXM1 →	+1.439	+0.385	<.001	<.001	3	9
BRCA	CDCA3 →	+0.840	+0.223	<.001	<.001	3	9
BRCA	TROAP →	+1.266	+0.372	<.001	<.001	3	9
LSCC	TICRR →	+0.841	+0.282	<.001	<.001	3	9
UCEC	EME1 →	+0.815	+0.175	<.001	<.001	3	9

Each partner links to its Q-omics profile. Showing the 6 strongest of 17,408 associations by consensus.

Exploration

NOC4L survival (RNA) · tumor vs normal (RNA) · all NOC4L data types