NOC2LP2

mutation — cross-omics
Cross-omicsMUTATION → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NOC2LP2 mutation is significantly associated with the RNA expression of many other genes, with 806 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOC2LP2-associated genes across cancer lineages are DUX4L16, SMIM11P1, and TAS2R9. Each is linked with NOC2LP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOC2LP2-to-partner and partner-to-NOC2LP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC2LP2→partner) and Y-score (partner→NOC2LP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
LUSCDUX4L16 →+0.015+2.993<.001.00633
SKCMSMIM11P1 →+0.069+2.053.001.00933
READTAS2R9 →+0.085+5.421<.001.00532
READRN7SL25P →+0.308+5.925<.001.00232
READRN7SL811P →+0.154+5.653<.001.00332
UCECRNU6-669P →+0.279+2.437<.001.00132
Each partner links to its Q-omics profile. Showing the 6 strongest of 806 associations by consensus.

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