NOC2LP2

mutation — cross-omics
Cross-omicsMUTATION → PROTEIN-RPPAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NOC2LP2 mutation is significantly associated with the total protein of many other genes, with 24 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOC2LP2-associated genes across cancer lineages are Annexin-1, 4E-BP1, and ACC1. Each is linked with NOC2LP2 in more than 2 cancer types. Because this analysis shows association rather than direction, both NOC2LP2-to-partner and partner-to-NOC2LP2 results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC2LP2→partner) and Y-score (partner→NOC2LP2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
UCECAnnexin-1 →+0.569+2.459.005.01832
LUAD4E-BP1 →+0.395+2.820.010.03523
UCECACC1 →+0.329+3.183.021.00932
UCECSTAT5a →+0.319+2.321.042.03432
UCECJNK_pT183_Y185 →-0.171-1.986.009.01031
UCECKu80 →+0.209+1.598.024.02231
Each partner links to its Q-omics profile. Showing the 6 strongest of 24 associations by consensus.

Exploration