Across TCGA patient cohorts, NOC2L mutation is significantly associated with the RNA expression of many other genes, with 3,407 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOC2L-associated genes across cancer lineages are TRGJP2, BRWD1P3, and MIR8064. Each is linked with NOC2L in more than 3 cancer types. Because this analysis shows association rather than direction, both NOC2L-to-partner and partner-to-NOC2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC2L→partner) and Y-score (partner→NOC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
COAD	TRGJP2 →	+0.703	+3.226	<.001	.002	3	4
BLCA	BRWD1P3 →	+0.419	+3.234	.005	.009	3	3
BLCA	MIR8064 →	+0.308	+2.589	.004	.005	3	3
HNSC	RNA5SP297 →	+0.394	+4.069	<.001	.001	3	3
UCEC	HYOU1 →	+0.610	+2.807	.001	.003	3	2
UCEC	INCENP →	+0.549	+2.031	.003	.004	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,407 associations by consensus.

Exploration

NOC2L survival (RNA) · tumor vs normal (RNA) · all NOC2L data types