Across TCGA patient cohorts, NOC2L mutation is significantly associated with the total protein of many other genes, with 22 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NOC2L-associated genes across cancer lineages are eIF4E, p62 Lck ligand, and PCNA. Each is linked with NOC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both NOC2L-to-partner and partner-to-NOC2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC2L→partner) and Y-score (partner→NOC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	eIF4E →	+0.184	+3.335	.013	.005	3	2
UCEC	p62 Lck ligand →	+0.424	+2.125	<.001	.010	3	2
UCEC	PCNA →	+0.209	+2.392	.006	<.001	3	2
UCEC	VHL →	-0.613	-1.415	.010	.043	3	2
UCEC	YAP →	+0.111	+3.183	.035	.009	3	2
UCEC	ATM →	-0.491	-2.000	.002	.003	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 22 associations by consensus.

Exploration

NOC2L survival (RNA) · tumor vs normal (RNA) · all NOC2L data types