Across TCGA cell cohorts, NOC2L mutation is significantly associated with the RNA expression of many other genes, with 146 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOC2L-associated genes across cancer lineages are C12orf57, OR2T5, and SFT2D3. Each is linked with NOC2L in more than 1 cancer types. Because this analysis shows association rather than direction, both NOC2L-to-partner and partner-to-NOC2L results are reported.

Each partner links to its own Q-omics profile.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NOC2L→partner) and Y-score (partner→NOC2L) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	C12orf57 →	+0.908	+3.364	.001	.002	3	2
BREAST	OR2T5 →	+0.025	+4.781	<.001	.003	3	2
BLOOD_Leukemia	SFT2D3 →	+0.482	+3.187	<.001	.001	3	2
BONE	LCE3A →	+0.270	+4.169	<.001	.008	3	1
BONE	BSPH1 →	+0.055	+4.169	<.001	.008	3	1
BONE	SPINK9 →	+0.058	+4.307	.003	.004	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 146 associations by consensus.

Exploration

NOC2L survival (RNA) · tumor vs normal (RNA) · all NOC2L data types