NOA1

Across TCGA cell cohorts, NOA1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,136 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NOA1-associated GO terms across cancer lineages are RNA folding, Mitochondrial ribosome assembly, and Mitochondrial small ribosomal subunit assembly. Each is linked with NOA1 in more than 16 cancer types. Because this analysis shows association rather than direction, both NOA1-to-partner and partner-to-NOA1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, RNA folding grouped by NOA1-low versus NOA1-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NOA1→partner) and Y-score (partner→NOA1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	RNA folding →	+0.158	+0.802	<.001	.001	3	17
STOMACH	Mitochondrial ribosome assembly →	+0.090	+0.506	<.001	.005	3	12
CNS	Mitochondrial small ribosomal subunit assembly →	+0.096	+0.894	<.001	<.001	3	12
LUNG_SCLC	'de novo' IMP biosynthetic process →	+0.152	+0.499	<.001	.007	3	11
STOMACH	Regulation of lipophagy →	+0.124	+0.569	.001	.002	3	8
STOMACH	Positive regulation of lipophagy →	+0.124	+0.569	.001	.002	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,136 associations by consensus.

RNA folding by NOA1 expression — LIVER

Explore this box plot interactively →