NNT-AS1

Across TCGA pan-cancer cohorts, NNT-AS1 RNA is linked to patient survival in 25 of 34 cancer types, making it the most broadly survival-associated NNT-AS1 data layer.

The strongest signal is observed in kidney renal clear cell carcinoma (KIRC), where higher NNT-AS1 RNA is associated with better disease-free survival. In most high-consensus cancer types, elevated NNT-AS1 expression acts as an unfavorable survival marker, although some lineages such as KIRC and UCS show a favorable association.

KIRC, UCS, and READ are the cancer types where NNT-AS1 RNA most reproducibly stratifies survival.

RNA survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
KIRC	DFS	Median	All	0.734	0.525	<.001	96	view →
UCS	DFS	Tertile	III,IV	0.618	0.189	<.001	52	view →
READ	DFS	Tertile	II,III,IV	0.692	0.195	.005	39	view →
SKCM	DFS	Quartile	All	0.717	0.510	.001	34	view →
LIHC	DFS	Tertile	All	0.430	0.604	<.001	31	view →
KIRP	DFS	Quartile	All	1.000	0.536	.001	28	view →
MESO	OS	Median	All	0.685	0.332	.007	22	view →
LGG	DFS	Tertile	All	0.572	0.271	<.001	20	view →
HNSC	DFS	Quartile	IV	0.489	0.218	<.001	17	view →
PRAD	DFS	Quartile	All	0.923	0.738	.002	14	view →
PAAD	OS	Quartile	All	0.585	0.256	.012	9	view →
LUAD	DFS	Median	All	0.814	0.714	.020	9	view →

Pink = unfavorable, green = favorable. Showing the 12 strongest of 25 lineages.

NNT-AS1–KIRC (DFS)

Open the KIRC breakdown →