NNAT

Across TCGA cell cohorts, NNAT RNA expression is significantly associated with the go_rna of many other GO terms, with 4,063 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NNAT-associated GO terms across cancer lineages are Regulation of mRNA processing, Regulation of mRNA splicing, via spliceosome, and Regulation of mRNA catabolic process. Each is linked with NNAT in more than 17 cancer types. Because this analysis shows association rather than direction, both NNAT-to-partner and partner-to-NNAT results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of mRNA processing grouped by NNAT-low versus NNAT-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NNAT→partner) and Y-score (partner→NNAT) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Regulation of mRNA processing →	+0.092	+2.176	<.001	<.001	3	18
SOFT_TISSUE	Regulation of mRNA splicing, via spliceosome →	+0.096	+2.201	<.001	<.001	3	16
SOFT_TISSUE	Regulation of mRNA catabolic process →	+0.081	+3.983	<.001	<.001	3	16
UPPER_AERODIGESTIVE_TRACT	mRNA transport →	+0.105	+1.542	<.001	<.001	3	15
BLOOD_Lymphoma	mRNA catabolic process →	+0.064	+0.752	<.001	<.001	3	15
SOFT_TISSUE	RNA export from nucleus →	+0.124	+3.252	<.001	<.001	3	15

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,063 associations by consensus.

Regulation of mRNA processing by NNAT expression — SOFT_TISSUE

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