NMUR2

Across TCGA patient cohorts, NMUR2 mutation is significantly associated with the total protein of many other genes, with 29 significant associations in total. SKCM shows the largest number of these associations.

The most reproducible NMUR2-associated genes across cancer lineages are 14-3-3_beta, Caspase-8, and Cyclin-B1. Each is linked with NMUR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMUR2-to-partner and partner-to-NMUR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, 14-3-3_beta grouped by NMUR2-low versus NMUR2-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMUR2→partner) and Y-score (partner→NMUR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	14-3-3_beta →	-0.090	-2.432	.013	.018	3	2
UCEC	Caspase-8 →	-0.250	-3.780	.005	<.001	3	2
UCEC	Cyclin-B1 →	+0.477	+1.925	.018	.005	3	2
UCEC	JNK2 →	+0.236	+2.807	<.001	<.001	3	2
UCEC	MEK1 →	+0.450	+2.807	<.001	<.001	3	2
UCEC	p62 Lck ligand →	+0.357	+1.925	.002	.005	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 29 associations by consensus.

14-3-3_beta by NMUR2 expression — UCEC

Explore this box plot interactively →