NMUR2

Across TCGA cell cohorts, NMUR2 mutation is significantly associated with the RNA expression of many other genes, with 21 significant associations in total. SKIN shows the largest number of these associations.

The most reproducible NMUR2-associated genes across cancer lineages are TMEM244, HCRTR2, and TMEM132C. Each is linked with NMUR2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMUR2-to-partner and partner-to-NMUR2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TMEM244 grouped by NMUR2-low versus NMUR2-high in SKIN.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMUR2→partner) and Y-score (partner→NMUR2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKIN	TMEM244 →	+0.634	+2.467	<.001	.008	3	2
BLOOD_Leukemia	HCRTR2 →	+0.010	+4.551	.007	.004	3	1
BLOOD_Leukemia	TMEM132C →	+1.146	+4.551	<.001	.004	3	1
BLOOD_Leukemia	MC2R →	+0.004	+4.969	<.001	.003	3	1
BLOOD_Leukemia	KRTAP12-3 →	+0.058	+4.539	<.001	.007	3	1
LARGE_INTESTINE	DCDC2C →	+0.097	+4.273	<.001	.006	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 21 associations by consensus.

TMEM244 by NMUR2 expression — SKIN

Explore this box plot interactively →