NMUR1

Across TCGA patient cohorts, NMUR1 mutation is significantly associated with the total protein of many other genes, with 48 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMUR1-associated genes across cancer lineages are TFRC, eEF2, and Ku80. Each is linked with NMUR1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMUR1-to-partner and partner-to-NMUR1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TFRC grouped by NMUR1-low versus NMUR1-high in SKCM.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMUR1→partner) and Y-score (partner→NMUR1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TFRC →	+0.728	+3.000	.008	.034	3	2
UCEC	eEF2 →	+0.458	+1.807	.001	.027	3	2
UCEC	Ku80 →	+0.231	+2.335	.018	.003	3	2
UCEC	N-Ras →	-0.176	-2.986	<.001	.001	3	2
UCEC	Paxillin →	+0.293	+2.472	.006	.010	3	2
SKCM	HSP70 →	-0.545	-2.987	.038	.035	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 48 associations by consensus.

TFRC by NMUR1 expression — SKCM

Explore this box plot interactively →