NMU

Across TCGA cell cohorts, NMU RNA expression is significantly associated with the go_rna of many other GO terms, with 3,489 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NMU-associated GO terms across cancer lineages are Regulation of gastric motility, Regulation of gastro-intestinal system smooth muscle contraction, and Positive regulation of gastro-intestinal system smooth muscle contraction. Each is linked with NMU in more than 19 cancer types. Because this analysis shows association rather than direction, both NMU-to-partner and partner-to-NMU results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Regulation of gastric motility grouped by NMU-low versus NMU-high in STOMACH.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMU→partner) and Y-score (partner→NMU) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STOMACH	Regulation of gastric motility →	+2.068	+4.518	<.001	<.001	3	20
STOMACH	Regulation of gastro-intestinal system smooth muscle contraction →	+2.221	+4.518	<.001	<.001	3	19
STOMACH	Positive regulation of gastro-intestinal system smooth muscle contraction →	+2.221	+4.518	<.001	<.001	3	19
LUNG_NSCLC_LUSC	Negative regulation of gastric acid secretion →	+2.166	+2.974	<.001	<.001	3	19
OESOPHAGUS	Gastric acid secretion →	+1.773	+3.007	<.001	<.001	3	17
LUNG_NSCLC_LUSC	Negative regulation of eating behavior →	+1.231	+2.952	.005	<.001	3	16

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,489 associations by consensus.

Regulation of gastric motility by NMU expression — STOMACH

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