NMT2

Across TCGA cell cohorts, NMT2 mutation is significantly associated with the RNA expression of many other genes, with 697 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMT2-associated genes across cancer lineages are ANKRD54, KDELR3, and CBY1. Each is linked with NMT2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMT2-to-partner and partner-to-NMT2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ANKRD54 grouped by NMT2-low versus NMT2-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMT2→partner) and Y-score (partner→NMT2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ANKRD54 →	+0.507	+2.588	.001	.004	3	1
LARGE_INTESTINE	KDELR3 →	+1.057	+3.169	.001	.009	3	1
LARGE_INTESTINE	CBY1 →	+0.677	+3.330	<.001	.002	3	1
LARGE_INTESTINE	JOSD1 →	+0.563	+3.321	.001	.003	3	1
LARGE_INTESTINE	MIOX →	+0.303	+3.257	<.001	.002	3	1
LARGE_INTESTINE	HMGXB4 →	+0.490	+2.502	.008	.005	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 697 associations by consensus.

ANKRD54 by NMT2 expression — LARGE_INTESTINE

Explore this box plot interactively →