NMT1

Across TCGA patient cohorts, NMT1 mutation is significantly associated with the RNA expression of many other genes, with 2,555 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMT1-associated genes across cancer lineages are ZNF852, FANCB, and FTMT. Each is linked with NMT1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMT1-to-partner and partner-to-NMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ZNF852 grouped by NMT1-low versus NMT1-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMT1→partner) and Y-score (partner→NMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	ZNF852 →	+0.330	+2.354	.002	<.001	3	2
UCEC	FANCB →	+0.488	+3.807	<.001	<.001	3	2
UCEC	FTMT →	+0.197	+1.948	<.001	.001	3	2
UCEC	C5orf24 →	+0.505	+2.321	.004	.001	3	2
UCEC	ZNF765 →	+0.305	+2.724	.007	.003	3	2
UCEC	ZNF782 →	+0.381	+3.872	.001	<.001	3	2

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,555 associations by consensus.

ZNF852 by NMT1 expression — UCEC

Explore this box plot interactively →