NMT1

Across TCGA cell cohorts, NMT1 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,289 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMT1-associated GO terms across cancer lineages are Metaphase/anaphase transition of cell cycle, Regulation of protein localization to nucleus, and U2-type prespliceosome assembly. Each is linked with NMT1 in more than 12 cancer types. Because this analysis shows association rather than direction, both NMT1-to-partner and partner-to-NMT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Metaphase/anaphase transition of cell cycle grouped by NMT1-low versus NMT1-high in BLOOD_Lymphoma.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMT1→partner) and Y-score (partner→NMT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BLOOD_Lymphoma	Metaphase/anaphase transition of cell cycle →	+0.118	+0.811	<.001	<.001	3	13
KIDNEY	Regulation of protein localization to nucleus →	+0.076	+0.877	.007	.002	3	11
STOMACH	U2-type prespliceosome assembly →	+0.088	+0.481	.006	.005	3	11
URINARY_TRACT	Protein depolymerization →	+0.122	+0.683	<.001	.005	3	11
BLOOD_Lymphoma	RNA export from nucleus →	+0.058	+0.555	<.001	<.001	3	11
BLOOD_Lymphoma	Metaphase/anaphase transition of mitotic cell cycle →	+0.113	+0.811	<.001	<.001	3	11

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,289 associations by consensus.

Metaphase/anaphase transition of cell cycle by NMT1 expression — BLOOD_Lymphoma

Explore this box plot interactively →