NMRK2

Across TCGA patient cohorts, NMRK2 protein abundance is significantly associated with the RNA expression of many other genes, with 1,250 significant associations in total. HNSC shows the largest number of these associations.

The most reproducible NMRK2-associated genes across cancer lineages are DMC1, CD160, and TSKS. Each is linked with NMRK2 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMRK2-to-partner and partner-to-NMRK2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMRK2 versus DMC1 in CCRCC, with a Pearson correlation of 0.95.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRK2→partner) and Y-score (partner→NMRK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
CCRCC	DMC1 →	+1.225	+3.585	.004	.008	3	1
CCRCC	CD160 →	-1.140	-3.585	.009	.008	3	1
CCRCC	TSKS →	-0.500	-3.585	.003	.008	3	1
CCRCC	TRIP12 →	-0.805	-3.585	.001	.008	3	1
CCRCC	DTYMK →	-0.450	-3.585	.007	.008	3	1
CCRCC	PSMD1 →	-0.629	-3.585	.009	.008	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,250 associations by consensus.

NMRK2 vs DMC1 — CCRCC

Explore this scatter interactively →