NMRK2

Across TCGA cell cohorts, NMRK2 RNA expression is significantly associated with the go_rna of many other GO terms, with 1,865 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NMRK2-associated GO terms across cancer lineages are Positive regulation of DNA-templated transcription, elongation, Golgi vesicle transport, and ATP biosynthetic process. Each is linked with NMRK2 in more than 4 cancer types. Because this analysis shows association rather than direction, both NMRK2-to-partner and partner-to-NMRK2 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of DNA-templated transcription, elongation grouped by NMRK2-low versus NMRK2-high in SOFT_TISSUE.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRK2→partner) and Y-score (partner→NMRK2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Positive regulation of DNA-templated transcription, elongation →	+0.054	+0.704	<.001	.001	3	5
BLOOD_Lymphoma	Golgi vesicle transport →	+0.042	+0.139	<.001	.009	3	5
LUNG_SCLC	ATP biosynthetic process →	+0.089	+0.725	<.001	.004	3	5
LUNG_SCLC	Purine nucleoside triphosphate biosynthetic process →	+0.090	+0.705	<.001	.005	3	5
LUNG_SCLC	Purine ribonucleoside triphosphate biosynthetic process →	+0.090	+0.705	<.001	.005	3	5
SOFT_TISSUE	Peripheral nervous system axon regeneration →	-0.466	-1.136	<.001	.005	3	4

Each partner links to its Q-omics profile. Showing the 6 strongest of 1,865 associations by consensus.

Positive regulation of DNA-templated transcription, elongation by NMRK2 expression — SOFT_TISSUE

Explore this box plot interactively →