NMRAL1

Across TCGA pan-cancer cohorts, NMRAL1 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NMRAL1 data layer compared with 22 for mass-spec protein and 1 for mutation status.

The strongest signal is observed in pancreatic ductal adenocarcinoma (PDAC), where higher NMRAL1 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NMRAL1 expression acts as an unfavorable survival marker, although some lineages such as PDAC and HNSC show a favorable association.

PDAC, LSCC, and GBM are the cancer types where NMRAL1 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
PDAC	DFS	Tertile	All	0.579	0.275	<.001	71	view →
LSCC	DFS	Quartile	III,IV	0.306	0.907	.004	15	view →
GBM	DFS	Quartile	All	0.319	0.521	.009	8	view →
HNSC	DFS	Quartile	III,IV	1.000	0.205	.036	2	view →
CCRCC	OS	Median	All	0.762	0.901	.033	2	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NMRAL1–PDAC (DFS)

Open the PDAC breakdown →