NMRAL1

mutation — cross-omics
Cross-omicsMUTATION → IMMUNEPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NMRAL1 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. KIRC shows the largest number of these associations.

The most reproducible NMRAL1-associated genes across cancer lineages are CD4+ Tcm, CD4+ Tem, and Tregs. Each is linked with NMRAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMRAL1-to-partner and partner-to-NMRAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, CD4+ Tcm grouped by NMRAL1-low versus NMRAL1-high in HNSC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRAL1→partner) and Y-score (partner→NMRAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
HNSCCD4+ Tcm →+0.007+5.468<.001.04331
KIRCCD4+ Tem →+0.021+4.241.025.02531
KIRCTregs →+0.023+4.673.002.01431
Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

CD4+ Tcm by NMRAL1 expression — HNSC

Box plot of CD4+ Tcm in NMRAL1-low vs NMRAL1-high samples in HNSC.

Explore this box plot interactively →

Exploration