NMRAL1

Across TCGA cell cohorts, NMRAL1 mutation is significantly associated with the RNA expression of many other genes, with 6 significant associations in total. LARGE_INTESTINE shows the largest number of these associations.

The most reproducible NMRAL1-associated genes across cancer lineages are ETNPPL, IFIT1B, and OR51T1. Each is linked with NMRAL1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NMRAL1-to-partner and partner-to-NMRAL1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, ETNPPL grouped by NMRAL1-low versus NMRAL1-high in LARGE_INTESTINE.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMRAL1→partner) and Y-score (partner→NMRAL1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LARGE_INTESTINE	ETNPPL →	+0.186	+3.021	.003	.003	3	1
LARGE_INTESTINE	IFIT1B →	+0.022	+3.145	.007	.004	3	1
BLOOD_Leukemia	OR51T1 →	+0.071	+4.922	<.001	.009	3	1
BLOOD_Leukemia	GSG1L2 →	+0.058	+5.969	<.001	.001	3	1
LARGE_INTESTINE	MSH4 →	+0.271	+3.464	.001	.004	2	1
LARGE_INTESTINE	CACNA2D1 →	+0.897	+3.285	.004	.007	1	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 6 associations by consensus.

ETNPPL by NMRAL1 expression — LARGE_INTESTINE

Explore this box plot interactively →