NMNAT1P3

Across TCGA pan-cancer cohorts, NMNAT1P3 RNA differs between tumor and matched normal tissue in 5 of 18 cancer types tested, making tumor–normal expression one of NMNAT1P3’s most consistent transcriptional readouts.

The strongest signal is observed in breast invasive carcinoma (BRCA), where NMNAT1P3 RNA is repressed in tumor relative to normal tissue. In most cancer types NMNAT1P3 is over-expressed in tumor, although a few such as BRCA and KICH show the opposite, repressed pattern.

BRCA, KIRC, and KICH are the cancer types where NMNAT1P3 tumor–normal differential expression is most reproducible.

RNA tumor vs normal associations by lineage

Ranked by sampling consensus. Fold-change is the tumor-versus-normal difference in NMNAT1P3 RNA (log₂); positive values indicate higher expression in tumor. p-values are from the differential-expression test.

Lineage	Gender	Stage	Fold-change	p	Sampling consensus
BRCA	Female	All	−0.069	<.001	6	view →
KIRC	All	II,III,IV	+0.066	.009	4	view →
KICH	All	All	−0.056	.001	4	view →
HNSC	All	All	+0.049	.021	4	view →
LUAD	All	II,III,IV	−0.033	.011	1	view →

Pink = over-expressed in tumor, green = repressed in tumor. Showing the 5 strongest of 5 lineages.

NMNAT1P3–BRCA

Open the BRCA breakdown →