NMNAT1

Across TCGA patient cohorts, NMNAT1 RNA expression is significantly associated with the mutation status of many other genes, with 10,765 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NMNAT1-associated genes across cancer lineages are TP53, DOCK2, and TTN. Each is linked with NMNAT1 in more than 5 cancer types. Because this analysis shows association rather than direction, both NMNAT1-to-partner and partner-to-NMNAT1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, TP53 grouped by NMNAT1-low versus NMNAT1-high in SKCM.

RNA expression associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMNAT1→partner) and Y-score (partner→NMNAT1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SKCM	TP53 →	+3.071	+0.561	<.001	<.001	3	6
UCEC	DOCK2 →	+1.584	+0.315	<.001	<.001	3	4
BRCA	TTN →	-0.809	-0.159	.003	.001	3	3
LGG	EGFR →	+3.011	+0.379	<.001	<.001	3	3
UCEC	PCDHB4 →	+2.290	+0.413	<.001	<.001	3	3
COAD	RERE →	+3.459	+0.413	.005	.002	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 10,765 associations by consensus.

TP53 by NMNAT1 expression — SKCM

Explore this box plot interactively →