NMI

Across TCGA patient cohorts, NMI protein abundance is significantly associated with the RNA expression of many other genes, with 16,110 significant associations in total. GBM shows the largest number of these associations.

The most reproducible NMI-associated genes across cancer lineages are ETV7, OAS2, and IFIH1. Each is linked with NMI in more than 9 cancer types. Because this analysis shows association rather than direction, both NMI-to-partner and partner-to-NMI results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NMI versus ETV7 in BRCA, with a Pearson correlation of 0.67.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NMI→partner) and Y-score (partner→NMI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	ETV7 →	+1.380	+0.549	<.001	<.001	3	10
LSCC	OAS2 →	+1.489	+0.554	<.001	<.001	3	10
BRCA	IFIH1 →	+1.072	+0.516	<.001	<.001	3	10
OV	CD2 →	+1.971	+0.646	<.001	<.001	3	10
BRCA	CD80 →	+0.950	+0.530	<.001	<.001	3	10
HNSC	ZBP1 →	+1.329	+0.649	<.001	<.001	3	10

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,110 associations by consensus.

NMI vs ETV7 — BRCA

Explore this scatter interactively →