NMI

Across TCGA cell cohorts, NMI RNA expression is significantly associated with the go_rna of many other GO terms, with 5,421 significant associations in total. SOFT_TISSUE shows the largest number of these associations.

The most reproducible NMI-associated GO terms across cancer lineages are Cytolysis in another organism, Antigen processing and presentation of peptide antigen via MHC class I, and CD8-positive, alpha-beta T cell homeostasis. Each is linked with NMI in more than 14 cancer types. Because this analysis shows association rather than direction, both NMI-to-partner and partner-to-NMI results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Cytolysis in another organism grouped by NMI-low versus NMI-high in LIVER.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NMI→partner) and Y-score (partner→NMI) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LIVER	Cytolysis in another organism →	+2.233	+2.761	<.001	<.001	3	15
SOFT_TISSUE	Antigen processing and presentation of peptide antigen via MHC class I →	+0.215	+3.045	<.001	<.001	3	15
URINARY_TRACT	CD8-positive, alpha-beta T cell homeostasis →	+0.175	+1.338	.001	<.001	3	14
BREAST	Positive regulation of response to type II interferon →	+1.040	+2.513	<.001	<.001	3	14
BREAST	Positive regulation of type II interferon-mediated signaling pathway →	+1.040	+2.513	<.001	<.001	3	14
LUNG_SCLC	Death-inducing signaling complex assembly →	+0.316	+1.223	.004	.006	3	14

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,421 associations by consensus.

Cytolysis in another organism by NMI expression — LIVER

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