NME9

mass-spec protein & survival
Survivalmass-specKaplan–Meier · TCGA cohorts

Across TCGA pan-cancer cohorts, NME9 mass-spec protein is linked to patient survival in 3 of 34 cancer types, making it a survival-associated NME9 data layer compared with 21 for mass-spec protein and 7 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NME9 mass-spec protein is associated with better disease-free survival. In most high-consensus cancer types, elevated NME9 expression acts as an unfavorable survival marker, although some lineages such as UCEC and LSCC show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where NME9 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.
LineageMeasureSplitStageAUC1
high
AUC2
low
pSampling consensus
UCECDFSMedianAll1.0000.863.0068view →
LSCCDFSMedianIII,IV1.0000.795.0362view →
LUADOSMedianII,III,IV1.0000.910.0161view →
Pink = unfavorable, green = favorable. Showing the 3 strongest of 3 lineages.

NME9–UCEC (DFS)

Kaplan–Meier survival curve for NME9 mass-spec protein-high vs -low samples in UCEC.

Open the UCEC breakdown →

Exploration