NME8

Across TCGA patient cohorts, NME8 mutation is significantly associated with the RNA expression of many other genes, with 4,402 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NME8-associated genes across cancer lineages are SNHG30, SNHG21, and GPR3. Each is linked with NME8 in more than 3 cancer types. Because this analysis shows association rather than direction, both NME8-to-partner and partner-to-NME8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, SNHG30 grouped by NME8-low versus NME8-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME8→partner) and Y-score (partner→NME8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SNHG30 →	+0.614	+1.857	<.001	<.001	3	4
UCEC	SNHG21 →	+0.591	+2.443	<.001	<.001	3	4
SKCM	GPR3 →	+0.510	+1.813	.002	<.001	3	4
READ	RNU6-705P →	+0.505	+4.202	.002	.008	3	3
STAD	RNA5SP198 →	+0.385	+4.951	<.001	<.001	3	3
UCEC	POLE2 →	+0.651	+3.269	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 4,402 associations by consensus.

SNHG30 by NME8 expression — UCEC

Explore this box plot interactively →