NME8

Across TCGA cell cohorts, NME8 RNA expression is significantly associated with the go_rna of many other GO terms, with 665 significant associations in total. BLOOD_Leukemia shows the largest number of these associations.

The most reproducible NME8-associated GO terms across cancer lineages are Negative regulation of chromatin organization, Host-mediated suppression of symbiont invasion, and Regulation of thymocyte migration. Each is linked with NME8 in more than 2 cancer types. Because this analysis shows association rather than direction, both NME8-to-partner and partner-to-NME8 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Negative regulation of chromatin organization grouped by NME8-low versus NME8-high in LUNG_NSCLC_LUAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NME8→partner) and Y-score (partner→NME8) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_NSCLC_LUAD	Negative regulation of chromatin organization →	-0.058	-0.117	.002	.006	3	3
OVARY	Host-mediated suppression of symbiont invasion →	+0.076	+0.311	.007	.003	3	3
BLOOD_Leukemia	Regulation of thymocyte migration →	+0.977	+0.788	<.001	.004	3	3
BLOOD_Leukemia	Positive regulation of thymocyte migration →	+0.923	+0.839	<.001	.002	3	3
BLOOD_Leukemia	Astrocyte activation involved in immune response →	+0.129	+0.747	<.001	.001	3	3
BLOOD_Leukemia	Regulation of leukocyte migration →	+0.054	+0.655	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 665 associations by consensus.

Negative regulation of chromatin organization by NME8 expression — LUNG_NSCLC_LUAD

Explore this box plot interactively →