NME7

Across TCGA pan-cancer cohorts, NME7 mass-spec protein is linked to patient survival in 5 of 34 cancer types, making it a survival-associated NME7 data layer compared with 22 for mass-spec protein and 6 for mutation status.

The strongest signal is observed in uterine corpus endometrial carcinoma (UCEC), where higher NME7 mass-spec protein is associated with worse overall survival. In most high-consensus cancer types, elevated NME7 expression acts as an unfavorable survival marker, although some lineages such as PDAC show a favorable association.

UCEC, LSCC, and LUAD are the cancer types where NME7 mass-spec protein most reproducibly stratifies survival.

mass-spec protein survival associations by lineage

Ranked by sampling consensus. AUC1 and AUC2 indicate survival in the high- and low-expression groups, respectively; the lower AUC marks the poorer-surviving group. p-values are from the log-rank test.

Lineage	Measure	Split	Stage	AUC1 high	AUC2 low	p	Sampling consensus
UCEC	OS	Median	II,III,IV	0.580	1.000	.006	26	view →
LSCC	OS	Median	All	0.937	1.000	.011	20	view →
LUAD	DFS	Median	All	0.407	0.853	.005	5	view →
PDAC	DFS	Tertile	All	0.479	0.278	.042	2	view →
HNSC	DFS	Quartile	IV	0.528	0.806	.041	1	view →

Pink = unfavorable, green = favorable. Showing the 5 strongest of 5 lineages.

NME7–UCEC (OS)

Open the UCEC breakdown →