NME5

Across TCGA patient cohorts, NME5 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,208 significant associations in total. BRCA shows the largest number of these associations.

The most reproducible NME5-associated proteins across cancer lineages are WDR19, FBXW9, and CCDC149_S379. Each is linked with NME5 in more than 5 cancer types. Because this analysis shows association rather than direction, both NME5-to-partner and partner-to-NME5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME5 versus WDR19 in BRCA, with a Pearson correlation of 0.69.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NME5→partner) and Y-score (partner→NME5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	WDR19 →	+0.533	+2.164	<.001	<.001	3	6
OV	FBXW9 →	+0.542	+1.110	<.001	.001	3	6
HNSC	CCDC149_S379 →	+0.863	+0.736	<.001	<.001	3	6
BRCA	DDX21 →	-0.620	-1.289	<.001	<.001	3	6
BRCA	DDX21_S121 →	-0.659	-0.980	<.001	<.001	3	6
BRCA	LZTFL1 →	+0.673	+1.747	<.001	<.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,208 associations by consensus.

NME5 vs WDR19 — BRCA

Explore this scatter interactively →