NME5

Across TCGA patient cohorts, NME5 protein abundance is significantly associated with the protein abundance of many other proteins, with 16,816 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NME5-associated proteins across cancer lineages are SPA17, TTC25_S542, and GAS2L2_S316. Each is linked with NME5 in more than 3 cancer types. Because this analysis shows association rather than direction, both NME5-to-partner and partner-to-NME5 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME5 versus SPA17 in UCEC, with a Pearson correlation of 0.85.

protein abundance associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NME5→partner) and Y-score (partner→NME5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	SPA17 →	+1.321	+1.333	<.001	<.001	3	4
UCEC	TTC25_S542 →	+1.422	+1.311	<.001	<.001	3	4
OV	GAS2L2_S316 →	+2.630	+1.499	<.001	<.001	3	4
LUAD	RIBC1 →	+0.777	+0.770	<.001	<.001	3	3
UCEC	ROPN1L →	+1.096	+1.320	<.001	<.001	3	3
UCEC	RRAD →	+0.470	+1.008	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 16,816 associations by consensus.

NME5 vs SPA17 — UCEC

Explore this scatter interactively →