NME5

Across TCGA patient cohorts, NME5 mutation is significantly associated with the immune_cell of many other genes, with 3 significant associations in total. UCEC shows the largest number of these associations.

The most reproducible NME5-associated genes across cancer lineages are pDC, Erythrocytes, and Endothelial cells. Each is linked with NME5 in more than 1 cancer types. Because this analysis shows association rather than direction, both NME5-to-partner and partner-to-NME5 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, pDC grouped by NME5-low versus NME5-high in UCEC.

mutation associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME5→partner) and Y-score (partner→NME5) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
UCEC	pDC →	+0.054	+2.839	.043	.034	3	2
UCEC	Erythrocytes →	+0.028	+3.169	.038	.020	2	2
UCEC	Endothelial cells →	-0.049	-3.127	.018	.020	1	1

Each partner links to its Q-omics profile. Showing the 3 strongest of 3 associations by consensus.

pDC by NME5 expression — UCEC

Explore this box plot interactively →