NME4

Across TCGA patient cohorts, NME4 RNA expression is significantly associated with the protein abundance of many other proteins, with 11,788 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NME4-associated proteins across cancer lineages are PLCL2_S1113, ABI3, and GGA3_S159. Each is linked with NME4 in more than 5 cancer types. Because this analysis shows association rather than direction, both NME4-to-partner and partner-to-NME4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME4 versus PLCL2_S1113 in LSCC, with a Pearson correlation of -0.41.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NME4→partner) and Y-score (partner→NME4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	PLCL2_S1113 →	-0.514	-0.469	<.001	<.001	3	6
GBM	ABI3 →	-0.464	-0.323	<.001	<.001	3	5
LSCC	GGA3_S159 →	-0.288	-0.456	<.001	.002	3	5
UCEC	MYO18A →	-0.273	-0.664	<.001	<.001	3	5
HNSC	IL16 →	-0.632	-0.534	<.001	.001	3	5
HNSC	P4HA1 →	+0.580	+0.680	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 11,788 associations by consensus.

NME4 vs PLCL2_S1113 — LSCC

Explore this scatter interactively →