NME4

Across TCGA cell cohorts, NME4 protein abundance is significantly associated with the RNA expression of many other genes, with 2,469 significant associations in total. OVARY shows the largest number of these associations.

The most reproducible NME4-associated genes across cancer lineages are FXN, RPSA, and PUS1. Each is linked with NME4 in more than 1 cancer types. Because this analysis shows association rather than direction, both NME4-to-partner and partner-to-NME4 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME4 versus FXN in LUNG_SCLC, with a Pearson correlation of -0.70.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME4→partner) and Y-score (partner→NME4) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LUNG_SCLC	FXN →	-1.241	-1.330	<.001	.008	3	2
LUNG_SCLC	RPSA →	-1.120	-1.439	.001	.003	3	2
LUNG_SCLC	PUS1 →	-0.964	-1.330	.007	.008	3	2
LUNG_SCLC	NOC4L →	-0.757	-1.395	.001	.004	3	2
LUNG_SCLC	BCCIP →	-0.581	-1.395	.005	.004	3	1
LUNG_SCLC	SLC29A1 →	-0.561	-1.439	.009	.003	3	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,469 associations by consensus.

NME4 vs FXN — LUNG_SCLC

Explore this scatter interactively →