NME3

Across TCGA cell cohorts, NME3 protein abundance is significantly associated with the go_rna of many other GO terms, with 2,728 significant associations in total. BREAST shows the largest number of these associations.

The most reproducible NME3-associated GO terms across cancer lineages are Intraciliary transport involved in cilium assembly, Chondroitin sulfate proteoglycan metabolic process, and Glycoprotein biosynthetic process. Each is linked with NME3 in more than 4 cancer types. Because this analysis shows association rather than direction, both NME3-to-partner and partner-to-NME3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Intraciliary transport involved in cilium assembly grouped by NME3-low versus NME3-high in SOFT_TISSUE.

protein abundance associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NME3→partner) and Y-score (partner→NME3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
SOFT_TISSUE	Intraciliary transport involved in cilium assembly →	-0.165	-1.490	.003	.007	3	5
LUNG_SCLC	Chondroitin sulfate proteoglycan metabolic process →	+0.076	+1.466	<.001	.003	3	4
SKIN	Glycoprotein biosynthetic process →	+0.047	+1.772	.006	.005	3	4
PANCREAS	Regulation of leukocyte degranulation →	-0.131	-1.644	.004	.006	3	4
CNS	Receptor diffusion trapping →	-1.576	-1.764	<.001	<.001	3	3
CNS	Postsynaptic neurotransmitter receptor diffusion trapping →	-1.576	-1.764	<.001	<.001	3	3

Each partner links to its Q-omics profile. Showing the 6 strongest of 2,728 associations by consensus.

Intraciliary transport involved in cilium assembly by NME3 expression — SOFT_TISSUE

Explore this box plot interactively →