NME2P3

Across TCGA patient cohorts, NME2P3 RNA expression is significantly associated with the go_rna of many other GO terms, with 3,383 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NME2P3-associated GO terms across cancer lineages are Pyrimidine ribonucleotide biosynthetic process, UTP biosynthetic process, and Pyrimidine ribonucleoside triphosphate biosynthetic process. Each is linked with NME2P3 in more than 6 cancer types. Because this analysis shows association rather than direction, both NME2P3-to-partner and partner-to-NME2P3 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Pyrimidine ribonucleotide biosynthetic process grouped by NME2P3-low versus NME2P3-high in STAD.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NME2P3→partner) and Y-score (partner→NME2P3) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
STAD	Pyrimidine ribonucleotide biosynthetic process →	+0.036	+0.072	<.001	<.001	3	7
STAD	UTP biosynthetic process →	+0.037	+0.060	<.001	<.001	3	6
STAD	Pyrimidine ribonucleoside triphosphate biosynthetic process →	+0.038	+0.072	<.001	<.001	3	6
STAD	Protein maturation by iron-sulfur cluster transfer →	+0.044	+0.063	<.001	<.001	3	5
STAD	Aerobic respiration →	+0.051	+0.098	<.001	<.001	3	5
STAD	Electron transport chain →	+0.049	+0.103	<.001	<.001	3	5

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,383 associations by consensus.

Pyrimidine ribonucleotide biosynthetic process by NME2P3 expression — STAD

Explore this box plot interactively →