NME2P1

Across TCGA patient cohorts, NME2P1 protein abundance is significantly associated with the RNA expression of many other genes, with 94 significant associations in total. OV shows the largest number of these associations.

The most reproducible NME2P1-associated genes across cancer lineages are RNF168, FAM87A, and NUDCP1. Each is linked with NME2P1 in more than 1 cancer types. Because this analysis shows association rather than direction, both NME2P1-to-partner and partner-to-NME2P1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME2P1 versus RNF168 in OV, with a Pearson correlation of 0.74.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME2P1→partner) and Y-score (partner→NME2P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OV	RNF168 →	+1.646	+1.776	.005	.003	3	1
OV	FAM87A →	+0.166	+1.776	<.001	.003	3	1
OV	NUDCP1 →	+1.316	+1.776	.004	.003	3	1
OV	TIMP3 →	+3.530	+1.776	.001	.003	2	1
OV	MAP4K1 →	+0.490	+1.773	.001	.003	2	1
OV	COMP →	+2.986	+1.776	.002	.003	2	1

Each partner links to its Q-omics profile. Showing the 6 strongest of 94 associations by consensus.

NME2P1 vs RNF168 — OV

Explore this scatter interactively →