NME2

Across TCGA patient cohorts, NME2 RNA expression is significantly associated with the protein abundance of many other proteins, with 15,230 significant associations in total. LSCC shows the largest number of these associations.

The most reproducible NME2-associated proteins across cancer lineages are DDX52, KAT7_S57, and UTP15. Each is linked with NME2 in more than 7 cancer types. Because this analysis shows association rather than direction, both NME2-to-partner and partner-to-NME2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME2 versus DDX52 in LSCC, with a Pearson correlation of 0.64.

RNA expression associated proteins by consensus

Ranked by combined sampling and lineage consensus. X-score (NME2→partner) and Y-score (partner→NME2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner protein	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
LSCC	DDX52 →	+0.504	+0.640	<.001	<.001	3	8
LSCC	KAT7_S57 →	+0.821	+0.481	<.001	<.001	3	8
LSCC	UTP15 →	+0.391	+0.546	<.001	<.001	3	7
LSCC	UTP18 →	+0.385	+0.568	<.001	<.001	3	7
LUAD	WDR75 →	+0.393	+0.375	<.001	<.001	3	7
LSCC	COIL →	+0.452	+0.524	<.001	<.001	3	7

Each partner links to its Q-omics profile. Showing the 6 strongest of 15,230 associations by consensus.

NME2 vs DDX52 — LSCC

Explore this scatter interactively →