NME2

Across TCGA cell cohorts, NME2 protein abundance is significantly associated with the RNA expression of many other genes, with 3,350 significant associations in total. LUNG_SCLC shows the largest number of these associations.

The most reproducible NME2-associated genes across cancer lineages are UTP18, PTRH2, and GPD1L. Each is linked with NME2 in more than 8 cancer types. Because this analysis shows association rather than direction, both NME2-to-partner and partner-to-NME2 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME2 versus UTP18 in OVARY, with a Pearson correlation of 0.61.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME2→partner) and Y-score (partner→NME2) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner gene	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
OVARY	UTP18 →	+0.747	+1.210	.001	.001	3	9
CNS	PTRH2 →	+0.941	+1.564	<.001	<.001	3	8
BREAST	GPD1L →	+0.980	+0.741	.005	.002	3	7
PANCREAS	ANKRD40 →	+0.818	+1.107	<.001	.001	2	7
BREAST	NME1 →	+0.854	+0.977	.001	<.001	3	6
OESOPHAGUS	EIF3E →	+1.167	+1.782	.003	.001	3	6

Each partner links to its Q-omics profile. Showing the 6 strongest of 3,350 associations by consensus.

NME2 vs UTP18 — OVARY

Explore this scatter interactively →