NME1P1

Across TCGA patient cohorts, NME1P1 RNA expression is significantly associated with the go_rna of many other GO terms, with 5,008 significant associations in total. STAD shows the largest number of these associations.

The most reproducible NME1P1-associated GO terms across cancer lineages are Positive regulation of protein-containing complex assembly, Positive regulation of protein ubiquitination, and Nucleobase-containing compound transport. Each is linked with NME1P1 in more than 9 cancer types. Because this analysis shows association rather than direction, both NME1P1-to-partner and partner-to-NME1P1 results are reported.

Each partner links to its own Q-omics profile. The box plot shows the strongest example, Positive regulation of protein-containing complex assembly grouped by NME1P1-low versus NME1P1-high in BRCA.

RNA expression associated GO terms by consensus

Ranked by combined sampling and lineage consensus. X-score (NME1P1→partner) and Y-score (partner→NME1P1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.

Lineage	Partner GO term	X-score	Y-score	p(X)	p(Y)	Sampling consensus	Lineage consensus
BRCA	Positive regulation of protein-containing complex assembly →	+0.050	+0.022	<.001	.002	3	10
BRCA	Positive regulation of protein ubiquitination →	+0.057	+0.017	<.001	<.001	3	10
BRCA	Nucleobase-containing compound transport →	+0.061	+0.015	<.001	<.001	3	9
STAD	Negative regulation of DNA repair →	+0.050	+0.157	<.001	<.001	3	8
BRCA	Positive regulation of post-translational protein modification →	+0.063	+0.014	<.001	<.001	3	8
BRCA	Regulation of protein ubiquitination →	+0.055	+0.034	<.001	<.001	3	8

Each partner links to its Q-omics profile. Showing the 6 strongest of 5,008 associations by consensus.

Positive regulation of protein-containing complex assembly by NME1P1 expression — BRCA

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