NME1

protein abundance — cross-omics
Cross-omicsPROTEIN-MS → RNAPatientPairwise association · TCGA cohorts

Across TCGA patient cohorts, NME1 protein abundance is significantly associated with the RNA expression of many other genes, with 14,878 significant associations in total. OV shows the largest number of these associations.

The most reproducible NME1-associated genes across cancer lineages are SNED1, RASL12, and EFHD1. Each is linked with NME1 in more than 6 cancer types. Because this analysis shows association rather than direction, both NME1-to-partner and partner-to-NME1 results are reported.

Each partner links to its own Q-omics profile. The scatter plot shows the strongest example, NME1 versus SNED1 in OV, with a Pearson correlation of -0.49.

protein abundance associated genes by consensus

Ranked by combined sampling and lineage consensus. X-score (NME1→partner) and Y-score (partner→NME1) are standardized regression coefficients; both directions are reported because the association is undirected. p-values are from the association test.
LineagePartner geneX-scoreY-scorep(X)p(Y)Sampling consensusLineage consensus
OVSNED1 →-1.101-0.519<.001<.00137
CCRCCRASL12 →-0.954-0.283<.001.00136
UCECEFHD1 →-1.598-0.399<.001<.00136
OVLTBP2 →-1.011-0.346<.001<.00136
OVCNRIP1 →-0.787-0.282<.001.00836
OVENTPD1 →-0.709-0.540<.001<.00136
Each partner links to its Q-omics profile. Showing the 6 strongest of 14,878 associations by consensus.

NME1 vs SNED1 — OV

Per-sample scatter of NME1 vs SNED1 in OV (Pearson r = -0.49).

Explore this scatter interactively →

Exploration